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Disease Profile
Lyme disease
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
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Age of onset
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ICD-10
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Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
Borreliosis; Lyme borreliosis
Categories
Bacterial infections; Nervous System Diseases
Summary
Lyme disease is the most common tickborne
Symptoms
This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
Medical Terms | Other Names |
Learn More:
HPO ID
|
---|---|---|
30%-79% of people have these symptoms | ||
Joint inflammation
|
0001369 | |
Cranial nerve paralysis | 0006824 | |
Joint swelling | 0001386 | |
0001287 | ||
5%-29% of people have these symptoms | ||
Amaurosis fugax | 0100576 | |
Arrhythmia |
Abnormal heart rate
Heart rhythm disorders
Irregular heart beat
Irregular heartbeat
[ more ] |
0011675 |
Arthralgia |
Joint pain
|
0002829 |
Atrioventricular block |
Interruption of electrical communication between upper and lower chambers of heart
|
0001678 |
Dermal atrophy |
Skin degeneration
|
0004334 |
Encephalitis |
Brain inflammation
|
0002383 |
Fatigue |
Tired
Tiredness
[ more ] |
0012378 |
Fever | 0001945 | |
Headache |
Headaches
|
0002315 |
Insomnia |
Difficulty staying or falling asleep
|
0100785 |
Memory impairment |
Forgetfulness
Memory loss
Memory problems
Poor memory
[ more ] |
0002354 |
Muscle weakness |
Muscular weakness
|
0001324 |
Myalgia |
Muscle ache
Muscle pain
[ more ] |
0003326 |
Nausea and vomiting | 0002017 | |
Paresthesia |
Pins and needles feeling
Tingling
[ more ] |
0003401 |
Photophobia |
Extreme sensitivity of the eyes to light
Light hypersensitivity
[ more ] |
0000613 |
Skin nodule | 0200036 | |
Uveitis | 0000554 |
Organizations
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Supporting this Disease
-
American Lyme Disease Foundation (ALDF)
PO Box 466
Lyme, CT, CT 6371
E-mail: [email protected]
Website: https://www.aldf.com -
Global Lyme Alliance
1290 East Main Street, 3rd Floor
Stamford, CT 06902
Telephone: 203-969-1333
E-mail: [email protected]
Website: https://globallymealliance.org/ -
International Lyme and Associated Diseases Society (ILADS)
PO Box 341461
Bethesda, MD 20827-1461
Telephone: 301-263-1080
Fax: 301-560-5799
E-mail: [email protected]
Website: https://www.ilads.org/
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
In-Depth Information
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Lyme disease. Click on the link to view a sample search on this topic.
References
- Lyme Disease. Center for Disease Control and Prevention. August 2015; https://www.cdc.gov/lyme/index.html.
- Lyme disease. MedlinePlus. February 2014; https://www.nlm.nih.gov/medlineplus/ency/article/001319.htm.
- John O Meyerhoff, MD; Chief Editor: Herbert S Diamond, MD. Lyme Disease. Medscape Reference. January 2015; https://emedicine.medscape.com/article/330178-overview.