5 Facts you should know about

Adenoid cystic carcinoma

It is uncommon in the parotid gland while it is much more frequent in the submandibular gland and in minor salivary and mucinous glands

ACC has been traditionally subdivided into three histological groups - cribriform, tubular, and solid

Local recurrence occurs in approximately 50% of patients

Patients may survive for years with metastases because this tumor is generally well-differentiated and slow growing

Activation of the oncogenic transcription factor gene MYB is the key genomic event of ACC and seen in the vast majority of cases

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